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  Michael R.J. Forstner, Ph.D.

Phylogenetic Methods 5466

 

 

 

 

Class Syllabus - Fall

 

 

 

 

 

DAYS

TTH

 

PROFESSOR

Michael R.J. Forstner, Ph.D.

 

ROOM

TBA

 

PHONE

512-245-3362

 

TEXT 1

Inferring Phylogenies

By Joseph Felsenstein. Sinauer

 

EMAIL
WEBSITE

http://www.mikeforstner.com

 

TEXT 2

The Compleat Cladist

Download in first edition from http://www.nhm.ukans.edu/cc.html

 

OFFICE
OFFICE HOURS

SCI 240

TTH 1-2, W 9-12


Course Description and Objectives:

Reconstructing phylogenies is important in most fields of biology. Course emphasis is on practical data collection, management, and analysis. Laboratory exercises will introduce phylogenetic and DNA analysis software, and WWW resources. Students will learn how to address questions in their own research using phylogenetic methodologies

Grading Policy

The course will be evaluated by grades on reports from laboratory exercises. Each laboratory assignment is worth 100 points. Your lab assignment grade will be the sum of the points you earn during the semester divided by total points possible. Your final project is worth 25% of your final grade.

Attendance

Attendance is mandatory, however, I do not specifically deduct from your grade based on absences.

Assignment report

The results of your laboratory exercises are to be original works written by you for this course. You will be required to work with others on your analyses and in the process of learning the software and interpreting the results. In fact I expect your colleagues to be of constant assistance to you and you to them throughout the course. However, I also expect that the lab reports are each individuals own work. In the case of team reports I demand that all members on the team provide equal effort in the final report to me. Insure that this is true for each assignment. The paper must be delivered to me on time and in both typed and digital format to be accepted. The digital copies need to be in Word or WP format. Any departure from the due date or from the required format will result in letter grade deductions (1 letter grade per day with weekends and holidays inclusive) up to and including a grade of zero for the paper. Unless otherwise directed your laboratory assignments are due to my mailbox by 5pm the Friday of the week after being assigned. You will have a full week to complete each assignment, compose, edit, revise, and turn in each project report.

Reading assignment

Additional materials for the course will routinely be assigned and a significant amount of your own searching for relevant references required. Many of these works coincide with BIO4369 course materials, others will be needed as a consequence of a particular problem in a data file or analytical result. You are expected to have read and be prepared to integrate those materials as they become relevant in your reports. These are expected to enhance the scope of the course and to supplement the course text itself.

*Anyone requiring special assistance with disabilities, religious holidays, or university approved events please contact me immediately in order that any necessary accommodations may be made.

Please note that academic dishonesty is a serious offense and harsh penalties results. Please review the Academic Honesty policy which applies to all Texas State University students.

 

 

Class Syllabus

 
Class
 
 

 1

Introduction to the course

 

 2

Phylogenetic data and analyses

 

 3

MacClade introduction and first manipulations
Assignment 1 - Vertebrates and Cartoon datasets

 

 4

Using MacClade and managing data, manipulations in MacClade

     
 

 5

Entering data files and analyzing the matrix
Assignment 2 - Bembidion dataset
 

 6

Parsimony, outgroups, and character polarityl
 

 7

Introduction to Paup
Assignment 3 - Vertebrate and Cartoon datasets
 

 8

Parsimony in large data files, heuristic search methods
     
 

 9

Quantifying tree space
Assignment 4 - Bembidion dataset
 

10

Assessing support and evaluating phylogenetic signal
 

11

Support measures under parsimony
Assignment 5 � Colubridae dataset
 

12

Distance measures
     
 

13

Neighbor-joining and other distances analyses methods
Assignment 6 � Colubridae dataset
 

14

Phylogenetic software beyond the mainstream
 

15

Electronic resources search and execution
Assignment 7 � Elaphe dataset
 

16

Homology
     
 

17

Seqn alignment and homology I
Assignment 8 � Apicomplexan dataset
 

18

Electronic resources
 

19

12s alignments and homology II
Assignment 9 � 12s EMBL
 

20

Analyses of real data
     
 

21

Applications of methods to phylogenies
Assignment 9 (part two) � 12s EMBL
 

22

Maximum likelihood
 

23

Paup analyses using Maximum Likelihood
Assignment 10 - Elaphe
 

24

Library research retrieval and reading assignment -
     
 

25

Assignment 10 (part 2)
 

26

Interpreting your own data � and unique datasets
 

27

Final report due
 

28

Course Review
     
 

29

FINAL EXAM (comprehensive)